ATXN8OS and spinocerebellar ataxia type 8: Another microsatellite expansion disease in which lncRNAs are involved is the spinocerebellar ataxia type 8 (SCA8), an autosomal dominant disorder, characterized by bidirectional transcription of this expansion repeat from opposite strands, forming both a protein-coding transcript encoding a polyglutamine expansion, ATXN8, and a lncRNA transcript containing a CUG expansion, ATXN8OS [78].