First, we observed that activated NK cells in contact with GBM cells produced IFN-γ, as revealed by intracellular flow cytometry (Two tailed T-test, NK cells alone vs. NK cells+U87MG p=0.0043, n=5 and vs. HF66 p=0.0095, n=4), (Fig. 5A). The gene discussed is IFNG; the disease is glioblastoma.