TBX1 and breast carcinoma: Immunohistochemistry studies of human carcinoma biopsy specimens using a brachyury-specific monoclonal antibody (MAb) also demonstrated the expression of brachyury in human lung and breast carcinomas, both in primary tumors and metastases, while limited levels of brachyury were seen in testis and some specimens of thyroid, and no other adult normal tissues examined [6].