In addition, Yang et al. [33] studied on TGF-β-miR-34a-CCL22 signaling in hepatocellular carcinoma and revealed that the activity of TGF-β could suppress the expression of miR-34a, resulting in the enhanced production of the chemokine CCL22 and recruitment of Tregs. Here, TGFB1 is linked to hepatocellular carcinoma.