Given the similar roles of RUNX1 and RUNX2 in EOC progression (implications in EOC cell proliferation, migration and invasion) and the fact that all three RUNX proteins recognize common DNA sequence motifs [10], we analyzed the extent of overlap in differentially expressed genes/functional pathways following RUNX1 and RUNX2 knockdown in the SKOV3 ovarian adenocarcinoma cell line (analyses based on the data presented herein and our previous findings [25]). Here, RUNX1 is linked to ovarian adenocarcinoma.