The DUB, USP7, is a component of the DNA damage checkpoint which deubiquitinates p53 and Mdm2 to alter the stability and activity of p53 and is differentially expressed in non-small cell lung cancer [RW.ERROR - Unable to parse:&nbsp;&nbsp;}} {{142Pei,D.2012]. The gene discussed is TP53; the disease is non-small cell lung carcinoma.