When tested for non-motor deficits, results have differed based on promoter; animals expressing A30P α-synuclein from the Thy-1 promoter display cognitive deficits on the Morris water maze, while animals made using the PrP promoter do not (Freichel et al., 2007, Gomez-Isla et al., 2003). Here, SNCA is linked to Cognitive impairment.