TP53 and Treacher-Collins syndrome: Several genetic diseases, such as Diamond-Blackfan anemia, dyskeratosis congenita, and Treacher Collins syndrome, arise due to defects in ribosome production, and in a number of cases, this has been linked to the misregulation of p53 (Freed et al., 2010; Fumagalli and Thomas, 2011; Narla and Ebert, 2010).