CAV1 and neoplasm: Notable was that the combined covariate of Cav-1 and pERK-1/2 was able to identify patients at high risk of relapse even if the patients’ tumour displayed low grade (19/29 patients positive for the co-variate and relapsing early had grade 1 or 2 tumours) and/or low stage (11/29 had stage 1 or 2 tumours) disease.