A similar gradual increase occurred in the fractional excretion of NGAL in no-AKI versus transient AKI (P = 0.04) versus intrinsic AKI when AKI was defined based on the creatinine criterion but again, there was no significant difference between no-AKI and transient AKI (P = 0.49) when AKI was defined according to the diuresis criterion only (graphic illustration similar to Figure 3; not shown). This evidence concerns the gene LCN2 and acute kidney injury.