The human neuroblastoma SH-SY5Y cell line, which responds to retinoic acid [39], chronic NGF [40] or brain-derived neurotrophic factor (BDNF) [41], has also been used to verify if the nitration of proteins induced by nanotopography is specific for PC12 cells or can be considered a general effect in neuronal-like cell types. Here, BDNF is linked to neuroblastoma.