CXCL10 and chronic obstructive pulmonary disease: Having demonstrated that GW3965 inhibited LPS-induced CXCL10 protein secretion from alveolar macrophages, we investigated the effect of GW3965 on CXCL10 mRNA expression levels in macrophages from 8 S and 8 COPD patients in order to understand if this effect was also observed at the level of gene transcription.