Now, we observed that GW3965 (1 μM and 10 μM) did not change the expression levels of the known M2 associated genes HO-1, CD36, and MR in S and COPD macrophages (n=8 for both groups) after culture for 4, 24 and 48 h (Additional file 8). This evidence concerns the gene HMOX1 and chronic obstructive pulmonary disease.