Dr Gil Mor’s group identified a panel of 6 biomarkers, CA-125, osteopontin (OPN), insulin-like growth factor 2 (IGF-II), macrophage migration inhibitory factor (MIF), leptin and prolactin, which demonstrated a sensitivity of 95.3% and a specificity of 99.4% for the detection of ovarian cancer [8]. Here, SPP1 is linked to ovarian cancer.