In the subgroup analysis, the OR between the RASSF1A promoter methylation and ovarian cancer was 14.76 (95% CI = 5.73–38.01) in Asians and 6.85 (95% CI = 3.46–13.58) in Caucasians under the fixed-effects model. The gene discussed is RASSF1; the disease is ovarian carcinoma.