Examples of these viruses include Herpesviridae (HSV, HCMV), Papovaviridae (HPV), Flaviviridae (HCV, dengue), Paramyxoviridae (RSV) and Retroviridae (HIV, HTLV) [80]–[86].HIV gp120 recognizes HS through V3 loop that facilitates the attachment to the host cell and subsequent infection [86]–[89]. The gene discussed is ITIH4; the disease is infection.