The relative abundance of mouse ADAR2 did not significantly differ between the AAV9-injected and saline-injected AR2 mouse spinal cords (Fig 4A) but AAV9-Flag-hADAR2 infection induced 1.5-fold increase in the expression level of total ADAR2 mRNA in the spinal cords (Fig 4A) and brains (Supporting Information Fig S8). This evidence concerns the gene ADARB1 and infection.