LRRK2 and Parkinson disease: We then confirmed their specificity in vitro and in cell culture and demonstrated the presence of these phospho-epitopes in neuronal and glial lesions of 3R tauopathies (PiD), 4R tauopathies (PSP) and 3R + 4R tauopathies (AD) and in G2019S-LRRK2 carriers (PD).