Low serum adiponectin is commonly associated with dyslipidemia characterized by an increase in plasma levels of triglyceride (TG), LDL-CHO, apolipoprotein B-48, apolipoprotein C-III, chylomicrons and liver fat content, as well as a decrease in whole-body fat oxidation and HDL-CHO, independent of age, sex, body mass index, and diabetes [48, 49]. The gene discussed is APOB; the disease is diabetes mellitus.