RPS6KB1 and anaplastic large cell lymphoma: Sixty-six of the 71 (93%) ALCL tumors were p-p70S6K1 positive (p-p70S6K1+, Figure 1H), of which 42 (64%) were ALK+, 51 (77%) were p-AKT+, and 55 (83%) were p-mTOR+.