Sixty-four out of 71 (90%) ALCL tumors studied were p-4E-BP1 positive (p-4E-BP1+, Figure 1G), of which 40 (63%) were ALK+, 50 (78%) were p-AKT+, and 56 (88%) were p-mTOR+. The gene discussed is EIF4EBP1; the disease is anaplastic large cell lymphoma.