On the whole, except that ALK + ALCL was predominantly seen at a younger age, there was no correlation between the expression of ALK, p-AKT, p-mTOR and its two downstream molecules, p-4E-BP1 and p-70S6K1, and the risk factors of the age of onset, sex distribution, clinical B symptoms, primary lesion of the tumor, and the Ann Arbor stage of the disease (Table 4). Here, AKT1 is linked to anaplastic large cell lymphoma.