Eczema was strongly related to peanut allergy (odds ratio [OR] 3.20, 95% CI 1.30-7.93), and remained highly significant after adjustment for age, gender, other atopic diseases, setting, and level of peanut-specific IgE in multiple logistic regression analysis (adjusted OR [aOR] 3.33, 95% CI 1.07-10.35). The gene discussed is IGHE; the disease is peanut allergic reaction.