SOST and cardiovascular disorder: In conjunction with a recent publication by our group [34] serum sclerostin levels as measured with the present ELISA gradually increase with increasing cardiovascular disease burden: from controls without overt cardiovascular disease (0.76 ± 0.31 ng/mL), via non-renal patients with AVC (0.94 ± 0.45 ng/mL [34]), and via dialysis patients without AVC (1.35 ± 0.73 ng/mL) finally to dialysis patients with AVC (1.78 ± 0.84 ng/mL).