This demonstrated that three of the five CRC biomarkers could identify early-stage CRC (n = 36) from the controls (n = 36) in each control set; CEA (P = 0.0007), TFRC (P = 0.0303) and CA242 (P = 0.0311) (Table 2). This evidence concerns the gene CEACAM5 and colorectal carcinoma.