The risk of ischemic stroke can be influenced by genetic variation in the inflammatory agents, including Interleukin-33 (IL-33), interleukin 4 (IL-4), interleukin 6 (IL-6), intercellular adhesion molecule 1 (ICA M-1), E-selectin (E-sel), chemokine (C-C motif) ligand 11 (CCL11), lymphotoxin (LTA)[1,5,6]. This evidence concerns the gene SELE and ischemic stroke.