POMC and Adrenal insufficiency: Basal levels of growth hormone (GH), luteinizing hormone (LH), follicle stimulating hormone (FSH), plasma adrenocorticotropic hormone (ACTH), serum cortisol, thyroid stimulating hormone (TSH), free thyroxine (f-T4), testosterone, dehydroepiandrosterone (DHEA) and aldosterone were low, and endocrine function tests revealed hypo-responsiveness to stimulation, indicating panhypopituitarism and adrenal insufficiency (Table 2).