In active cirrhosis, MCP-1 expression was present in the portal tract, epithelial cells of regenerating bile ducts, and the active septa surrounding regenerating nodules.37 There was a direct relationship between MCP-1 expression and monocyte infiltration after acute liver injury.38 MCP-1 level was found to be higher in hepatic veins than in peripheral blood and occurred in severe cases of liver diseases.39 However, our result revealed that the circulating levels of MCP-1 in controls and diseased groups were comparable. This evidence concerns the gene CCL2 and liver disorder.