As an example, several members of the TRP family of ion channels, namely TRPC1, TRPC3, TRPC6, TRPV1, TRPV6, TRPM1, TRPM4, TRPM5, TRPM7, and TRPM8, show altered expression in cancer cells (Shapovalov et al., 2011). The gene discussed is TRPV1; the disease is cancer.