In the same trial another patient with end-stage chronic lymphocytic leukemia, treated with the bispecific F(ab’)2 antibody RFB-9 targeting saporin-S6 to the CD19 antigen (total of 10 mg of saporin-S6 complexed to 100 mg of anti-CD19 bispecific Ab, at days 0, +7, +28, +42), showed no therapeutic effect over 45 days. Here, CD19 is linked to B-cell chronic lymphocytic leukemia.