For example, in Model 1, the ORs for HE of 0.7, 2.2 and 3.6 for the FLG+/AD−, FLG−/AD+ and FLG+/AD+ subgroups correspond to RRs of, respectively, 0.7, 1.9, and 2.5. This evidence concerns the gene FLG and hereditary elliptocytosis.