Crude and adjusted Cox proportional hazard ratios (HRs) for mortality (Table 2) showed that patients from the low obestatin group had a significant crude HR (compared with patients with high obestatin) of 2.23 (95% CI: 1.17–4.24) for all-cause mortality and of 4.03 (95% CI: 1.27–12.76) for cardiovascular mortality that persisted after adjustment for age, gender, and diabetes status, but disappeared for cardiovascular mortality after further adjustments for history of past cardiovascular disease, dialysis vintage, and fat mass index. The gene discussed is GHRL; the disease is cardiovascular disorder.