STAT3 and cancer: Many reports today implicate STAT3-Ser in cell growth, proliferation, and survival, in the context of cancer (Plaza-Menacho et al., 2007; Qin et al., 2008; Aggarwal et al., 2009; Lacreusette et al., 2009; Yeh et al., 2009; Banerjee et al., 2010; Sekine et al., 2011; Villalva et al., 2011; Miyakoshi et al., 2012; Tkach et al., 2013; Yang et al., 2013), insulin and neurotrophin signaling (Ng et al., 2006; Kim et al., 2009), neurite outgrowth (Zhou and Too, 2011), and hypertension (Zouein et al., 2013).