In addition, recent studies have also shown that miR-26a [21], miR-221, miR-222 [22,23], miR-214 [24,25], miR-22 [26], and miR-106b~25 cluster [27] are either directly or indirectly involved in the regulation of PTEN expression, and interfere with tumor growth, progression and radioresistance. Here, PTEN is linked to neoplasm.