RUNX1 and chronic myelogenous leukemia, BCR-ABL1 positive: We first examined transcript levels of AML1 and its mutations, in clinical samples of 13 CML-BC (Table S1) and 5 CML-CP cases, 5 CML-BC cell lines (K562, MegO1, MegA2, Nalm1 and BV173), and 4 normal blood samples (3 BM and one PB).