NRGN and schizophrenia: Given the evidence for an association of NRGN with a diagnosis of schizophrenia and cortical development, as well as a reduced NRGN expression in frontal brain regions of schizophrenia patients, the aim of the present investigation was to understand the neurogenetic risk mechanisms of two common NRGN SNPs (rs12807809 and rs12541) and their haplotypes by studying intermediate phenotypes for schizophrenia: abnormal working memory-elicited DLPFC activity and reduced cortical thickness.