In keeping with previous studies regarding the induction of resistin, visfatin and leptin expression in inflammation-dependent mechanism and also considering these adipocytokines as the putative inflammatory mediators (reviewed in [25,26,31,37]) we found positive correlations between resistin, visfatin and leptin with circulating TNF-α, IL-1β and hs-CRP in MS patients. This evidence concerns the gene RETN and myeloid sarcoma.