In contrast, there was marked KPNA2 staining in the nuclei and cytoplasm of malignant cells in several skin tumors with different prognoses including Bowen’s disease, actinic keratosis, squamous cell carcinoma (SCC), Paget’s disease, Merkel cell carcinoma, and Mycosis fungoides. The gene discussed is KPNA2; the disease is squamous cell carcinoma.