Fasting increased EfnB1 mRNA level in WAT (Figure S4a), but streptozotocin (STZ)-induced insulin-deficiency had no influences on the mRNA level (Figure S4b), suggesting no direct effect for insulin on EfnB1 mRNA level in WAT. This evidence concerns the gene EFNB1 and hyperinsulinemic hypoglycemia, familial, 4.