Recent publications have also described a critical role for IL-1β and IL-17 -mediated inflammatory responses ultimately leading to the expression of immune mediators including keratinocyte chemoattractant (KC), macrophage inflammatory protein-2 (MIP-2) and granulocyte monocyte colony stimulating factor (GM-CSF) required to attract circulating neutrophils into the site of the infection along with c-kit+-progenitor cells which differentiate into mature neutrophils in the tissue [19]–[23]. This evidence concerns the gene IL1B and infection.