Accordingly, TiMa from meningiomas with isolated monosomy 22/del(22q) showed increased expression levels of several activation-associated markers with higher percentages of CD69+ (p≤0.009 vs diploid and complex tumors; Figure 3A) and CD63+ TiMa (p = 0.006 vs diploid cases; Figure 3B). This evidence concerns the gene CD63 and meningioma.