For example, FKBP5 promoter methylation at pre-treatment was significantly correlated with plasma cortisol levels (Figure 6A) such that higher FKBP5 promoter methylation was correlated with lower cortisol levels at pre-treatment, a result compatible with our previous findings of lower FKBP5 gene expression in PTSD (21). The gene discussed is FKBP5; the disease is post-traumatic stress disorder.