The predictions of our biological model, which is testable, are bolstered by recent genetic studies that have associated single nucleotide polymorphisms in the GAP-43 gene with autism (Allen-Brady et al., 2009), and identified its extended chromosomal region as an autism risk locus (Trikalinos et al., 2006; Szatmari et al., 2007). The gene discussed is GAP43; the disease is autism.