Analysis of targets that are affected by drugs according KEGG shows, that compounds affect MAPK and PI3K-Akt signaling pathway (all compounds), Caffeine metabolism (rapamycin, PDTC and 1400W) and Circadian rhythm pathways (rapamycin and PDTC) that are involved in lifespan control [5, 85, 86] and cancer development [87-89]. This evidence concerns the gene AKT1 and cancer.