A recent multiplex profiling of cytokines in the ascites obtained from 10 epithelial ovarian cancer patients has demonstrated enhanced expression of several factors including angiogenin, angiopoietin, GRO, ICAM-1, IL-6, IL-6R, IL-8, IL-10, leptin, MCP-1, MIF, NAP-2, osteoprotegerin (OPG), RANTES, TIMP-2, and urokinase plasminogen activator receptor (uPAR) (24). This evidence concerns the gene TNFRSF11B and ovarian carcinoma.