Both reduced E-cadherin and overexpression of Vimentin are observed during EMT and cancer progression (Berx & van Roy, 2009; Kang & Massague, 2004), leading to the shedding of the cancerous cells from the primary tumour (Hanahan & Weinberg, 2011; Satelli & Li, 2011; Schmalhofer et al, 2009; Thiery et al, 2009; Yilmaz & Christofori, 2009). Here, VIM is linked to cancer.