The loci chosen in our study harbor genes (ARHI, MEST, p16INK4A, KCNQ1, SLC5A8 and CDHs) acknowledged as important Tumour Suppressor Genes (TSGs) influencing cell growth, proliferation and apoptosis, and participating in the development and progression of many human tumours other than lung cancers (e.g. breast, ovarian, thyroid). This evidence concerns the gene KCNQ1 and lung cancer.