In hypersensitivity reactions to Aspergillus fumigatus, the presence of IgE antibody reactivity to Asp f 2, 4, and 6 may suggest allergic bronchopulmonary aspergillosis (ABPA) [72], whereas sensitization to Asp f 1 and/or Asp f 3 may be more indicative of allergic asthma [73]. The gene discussed is IGHE; the disease is allergic bronchopulmonary aspergillosis.