First, we examined the HCV J6/JFH1-P1 (passage 1) strain [15] and found that TSL, MLL, MMS and FFL inhibited HCV J6/JFH1-P1 infection with IC50 of 2.0, 2.1, 6.2 and 5.7 μg/ml, respectively. Here, KMT2A is linked to infection.