CASP3 and Behcet disease: In all organs investigated in this study we found elevated levels of activated Caspase 3 positive cells in BD as compared to LD, especially in the liver being significantly elevated even prior to organ retrieval indicating that BD induces apoptotic cell death due to the hemodynamic instability including short hypertensive phases at the onset of BD followed by a decline of blood pressure to normal tension or hypotension, what could cause poor organ perfusion and thereby inadequate oxygen supply despite of intensive donor care during 10 hours of BD.