However, they stated in their study that an increase of HSP 70 expression appears to be insufficient to counteract the detrimental effects of BD to the donor kidney[5]; therefore, taking in consideration the results of our study, the duration of BD especially in our large animal model, might negatively impact on the expression of genes of the HSP 70 family indicating that BD time should be kept as short as possible prior to organ retrieval but pharmacological intervention enhancing HSP expression prior to organ donation might be a valuable procedure to increase organ quality of BD kidneys[5]. The gene discussed is HSP90B2P; the disease is Behcet disease.