PTEN and neoplasm: As indicated in Table 4, SGC020, a PDGCX model with a PTEN exon 2-6 gene deletion and undetectable PTEN protein expression and SGC100, a PDGCX model harboring a PI3KCA H1047R activating mutation and positive PTEN staining, were both identified for AZD5363 anti-tumor efficacy study.