We further examined the role of NR4A2 in gastrin induced responses by employing the gastric adenocarcinoma cell line AGS-GR Gastrin induced a ~8-fold induction of NR4A2 mRNA in AGS-GR cells, followed by a rapid decrease to baseline after ~4 h of stimulation (Figure 1B). Here, GAST is linked to gastric adenocarcinoma.