Annexin V staining and FACS analysis of MM cell line INA-6 grown either with IL-6 or in co-cultures with HS-5 bone marrow stromal cells (BMSC) (Figure 3B), freshly isolated MM plasma cells from patients (Figure 3C) and MCL cell lines (Figure 3D) also demonstrated a cooperation between CK2 inhibitors and bortezomib in inducing cell apoptosis (p<0.05, n = 3–6). This evidence concerns the gene IL6 and Miyoshi myopathy.