Bcl2 family members expression analysis revealed that treatment with bortezomib plus CK2 inhibitors caused a stronger reduction of the anti-apoptotic Bcl2 and Mcl1 proteins and a higher accumulation of the pro-apoptotic Bak and Bax proteins in MM (Figure 4C) and MCL cells (Figure 4D). The gene discussed is BAX; the disease is mantle cell lymphoma.