In the case of MGUS and MM samples, double immunostaining for CD138 and either CK2α or CK2β is also shown in supplemental Figure S1 to emphasize the expression of the kinase in non malignant (Figure S1 A, B), pre-malignant MGUS (Figure S1 C, D) and malignant MM (Figure S1 E, F) bone marrow plasma cells. Here, CSNK2B is linked to Miyoshi myopathy.